Knowledge Hub
Researchers and physicians answer the questions most often asked about fat grafting and SVF (stromal vascular fraction). Each article answers one question, and every figure carries its source.
- PrinciplesAre SVF and stem cells the same thing?
What the stromal vascular fraction is made of, the adipose-derived stem cells within it, and why the precise name matters.
Stem Cell Research Center · 2026-10 - Reading dataWhere does the 77.48% average graft retention rate come from?
The data in the 2023 Annals of Plastic Surgery paper, the measurement time point (18 months), and what to watch for when reading the number.
Dr. Shin Dong-jin, Chief Director · 2026-10 - EquipmentAnswering "How many went in?" with a number
How the cell counter measures cell count and viability in every surgery, and what about 68 million to 99 million cells per injection means.
Stem Cell Research Center · 2026-10 - EquipmentWhy is a clean area needed?
What the pressure differential gauge, the insect light trap and "Authorized Personnel Only" mean.
Stem Cell Research Center · 2026-10 - ProcessWhy do researchers perform SVF isolation?
Why researchers with master's or doctoral degrees and more than 10 years of experience do it by hand, following the protocol.
Stem Cell Research Center · 2026-10 - StorageAt what temperature is cell banking done?
Cryogenic storage in a −196 °C liquid nitrogen tank.
Stem Cell Research Center · 2026-10 - ProcessHow SVF is isolated — the 5-step process
Purification at 300 g for 3 minutes, SVF isolation at 500 g for 3 minutes, cell counting, mixing at 9:0.5 and injection. The conditions stated in the paper and the process environment.
Stem Cell Research Center · 2026-10 - RegulationWhat designation as an Advanced Regenerative Medicine Institution does — and does not — mean
The difference between designation (Ministry of Health and Welfare) and licensing (MFDS), how to verify a designation number, and types of false or exaggerated advertising.
Stem Cell Research Center · 2026-10 - ProcessHow is graft retention data studied?
Collection → quantification and analysis → writing papers → journal publication. Four steps followed since 2007.
Stem Cell Research Center · 2026-10 - Reading dataWhat is the pre- and postoperative 3D precision check of graft retention?
How volume change is measured to quantify the graft retention rate. Opens a page on the SC301 Clinic website.
SC301 Clinic
Research notes reviewed by Dr. Shin Dong-jin, Chief Director
A separate blog run by SC301 Clinic (blog.medisgate.co.kr, in Korean). It holds 115 paper reviews and regulatory explainers, each listing its reviewer and references. These are the posts most closely related to the center.
- Research reviewLatest trends in SVF research — the direction of regenerative medicine in 2025–2026 papers (Korean)
Two meta-analyses (about 17 percentage points), the shift from enzymatic to mechanical isolation, cell dose, standardized measurement, and the amended Advanced Regenerative Bio Act.
Research notes · 2026-10-12 - ProcessThe SVF isolation process — step by step in a cell processing facility (Korean)
The 7-step process and the environment it requires. Includes a video of the extraction process.
Research notes · 2026-09-15 - PrinciplesThe physiology of graft take after fat grafting — the mechanisms of swelling and absorption (Korean)
The first 24 hours, 3 days to 12 weeks, how fast blood vessels connect, and the time curve in clinical data. 9 references.
Research notes · 2026-09-28 - PrinciplesWhy add stem cells to fat grafting — the biology of graft take (Korean)
VEGF secreted by ADSCs and angiogenesis. Evidence at three levels: cell experiments, comprehensive reviews and clinical studies.
Research notes · 2026-09-23 - Reading dataThe baseline for comparison — where conventional fat grafting without added SVF stands today (Korean)
A gap of 17.20 percentage points in a meta-analysis of 893 patients, 22.8 points with automated enzymatic isolation, and no difference in complications.
Research notes · 2026-09-22 - Reading dataThe basis for the 77.48% graft retention rate — SVF breast augmentation through an SCI paper (Korean)
Study overview, differences by cell count, tissue softness and arm movement, postoperative care principles stated in the paper, and 10 FAQs.
Research notes · 2026-09-07 - RegulationWhat is an Advanced Regenerative Medicine Institution — designation requirements and legal meaning (Korean)
How the designation system works, its requirements, how it differs from a cell processing facility license, regulatory changes in 2025–2026, and what to check when reading hospital information.
Research notes · 2026-10-07 - Reading dataFat grafting and SVF — how much is known about safety today (Korean)
An overall complication rate of about 4.8%, extremely rare embolism, and the principles of preventive technique.
Research notes · 2026-07-27 - PrinciplesADSCs (adipose-derived cells) — characteristics, research background and how they differ from SVF (Korean)
Three differentiation characteristics, the distinction between SVF and ADSCs, and the line between research and clinical use.
Research notes · 2026-07-16 - StorageStem cell banking — principles, purification and storage, and the state of research (Korean)
Non-cultured pure purification, storage at −196 °C, why storing at an earlier age is discussed, and current Korean regulations.
Research notes · 2026-07-08 - White paperSC301 Stem Cell White Paper (Korean)
23 chapters, from the definition and history of stem cells to SVF isolation, the one-stop system, papers, certifications and patents.
Research notes · 2026-06-23
Related articles on the clinic's main website
Articles from the SC301 Clinic website blog.
- PrinciplesSVF-assisted fat grafting: why do results differ?SC301 Clinic
- Principles"This is a stem cell (SVF) procedure too" — were you told PRP was stem cells?SC301 Clinic
- Reading dataSVF-assisted vs conventional fat grafting: the key factors behind the difference in graft retentionSC301 Clinic
Figures in these articles are sourced from the papers and data on the Research page. This site does not cover the methods, costs or consultations for any specific surgery.